Virtual Pharmacophore Screening Identifies Small‐Molecule Inhibitors of the Rev1‐CT/RIR Protein–Protein Interaction

© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Translesion synthesis (TLS) has emerged as a mechanism through which several forms of cancer develop acquired resistance to first-line genotoxic chemotherapies by allowing replication to continue in the presence of damaged DNA. Small molecules...

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Bibliographic Details
Main Authors: Dash, Radha C, Ozen, Zuleyha, McCarthy, Kaitlyn R, Chatterjee, Nimrat, Harris, Cynthia A, Rizzo, Alessandro A, Walker, Graham C, Korzhnev, Dmitry M, Hadden, M Kyle
Format: Article
Language:English
Published: Wiley 2021
Online Access:https://hdl.handle.net/1721.1/133551