Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

© Lu et al. Phosphatidylinositol 3-phosphate (PI(3)P) levels in Plasmodium falciparum correlate with tolerance to cellular stresses caused by artemisinin and environmental factors. However, PI(3)P function during the Plasmodium stress response was unknown. Here, we used PI3K inhibitors and antimalar...

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Bibliographic Details
Main Authors: Lu, Kuan-Yi, Pasaje, Charisse Flerida A, Srivastava, Tamanna, Loiselle, David R, Niles, Jacquin C, Derbyshire, Emily
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd 2021
Online Access:https://hdl.handle.net/1721.1/133586