Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin

Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin

© Megret et al. Loss of cellular homeostasis has been implicated in the etiology of several neurodegenerative diseases (NDs). However, the molecular mechanisms that underlie this loss remain poorly understood on a systems level in each case. Here, using a novel computational approach to integrate di...

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Bibliographic Details
Main Authors: Megret, Lucile, Gris, Barbara, Sasidharan Nair, Satish, Cevost, Jasmin, Wertz, Mary, Aaronson, Jeff, Rosinski, Jim, Vogt, Thomas F, Wilkinson, Hilary, Heiman, Myriam, Neri, Christian
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd 2021
Online Access:https://hdl.handle.net/1721.1/133745

Internet

https://hdl.handle.net/1721.1/133745

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