Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes

Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes

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© 2020, The Author(s). Due to breakthroughs in RNAi and genome editing methods in the past decade, it is now easier than ever to study fine details of protein synthesis in animal models. However, most of our understanding of translation comes from unicellular organisms and cultured mammalian cells....

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Bibliographic Details
Main Authors: Gerashchenko, Maxim V., Nesterchuk, Mikhail V., Smekalova, Elena M., Paulo, Joao A., Kowalski, Piotr S., Akulich, Kseniya A., Bogorad, Roman, Dmitriev, Sergey E., Gygi, Steven, Zatsepin, Timofei, Anderson, Daniel G., Gladyshev, Vadim N., Koteliansky, Victor E.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2022
Online Access:https://hdl.handle.net/1721.1/133989.2

Internet

https://hdl.handle.net/1721.1/133989.2

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