Nanoscale imaging of clinical specimens using pathology-optimized expansion microscopy

Nanoscale imaging of clinical specimens using pathology-optimized expansion microscopy

Expansion microscopy (ExM), a method for improving the resolution of light microscopy by physically expanding a specimen, has not been applied to clinical tissue samples. Here we report a clinically optimized form of ExM that supports nanoscale imaging of human tissue specimens that have been fixed...

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Bibliographic Details
Main Authors: Zhao, Yongxin, Bucur, Octavian, Irshad, Humayun, Chen, Fei, Weins, Astrid, Stancu, Andreea L, Oh, Eun-Young, DiStasio, Marcello, Torous, Vanda, Glass, Benjamin, Stillman, Isaac E, Schnitt, Stuart J, Beck, Andrew H, Boyden, Edward S
Other Authors: Massachusetts Institute of Technology. Media Laboratory
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/133995

Internet

https://hdl.handle.net/1721.1/133995

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