Role of nanoscale antigen organization on B-cell activation probed using DNA origami

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

© 2020, The Author(s), under exclusive licence to Springer Nature Limited. Vaccine efficacy can be increased by arraying immunogens in multivalent form on virus-like nanoparticles to enhance B-cell activation. However, the effects of antigen copy number, spacing and affinity, as well as the dimensio...

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Bibliographic Details
Main Authors: Veneziano, Rémi, Moyer, Tyson J, Stone, Matthew B, Wamhoff, Eike-Christian, Read, Benjamin J, Mukherjee, Sayak, Shepherd, Tyson R, Das, Jayajit, Schief, William R, Irvine, Darrell J, Bathe, Mark
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/134091

Internet

https://hdl.handle.net/1721.1/134091

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