BBB pathophysiology–independent delivery of siRNA in traumatic brain injury

Copyright © 2021 The Authors, some rights reserved. Small interfering RNA (siRNA)–based therapeutics can mitigate the long-term sequelae of traumatic brain injury (TBI) but suffer from poor permeability across the blood-brain barrier (BBB). One approach to overcoming this challenge involves treatmen...

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Bibliographic Details
Main Authors: Li, Wen, Qiu, Jianhua, Li, Xiang-Ling, Aday, Sezin, Zhang, Jingdong, Conley, Grace, Xu, Jun, Joseph, John, Lan, Haoyue, Langer, Robert, Mannix, Rebekah, Karp, Jeffrey M, Joshi, Nitin
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/134128