The chloroalkaloid (−)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants

The chloroalkaloid (−)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants

© 2020, The Author(s). Plant halogenated natural products are rare and harbor various interesting bioactivities, yet the biochemical basis for the involved halogenation chemistry is unknown. While a handful of Fe(II)- and 2-oxoglutarate-dependent halogenases (2ODHs) have been found to catalyze regio...

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Bibliographic Details
Main Authors: Kim, Colin Y, Mitchell, Andrew J, Glinkerman, Christopher M, Li, Fu-Shuang, Pluskal, Tomáš, Weng, Jing-Ke
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/134159

Internet

https://hdl.handle.net/1721.1/134159

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