The chloroalkaloid (−)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants
© 2020, The Author(s). Plant halogenated natural products are rare and harbor various interesting bioactivities, yet the biochemical basis for the involved halogenation chemistry is unknown. While a handful of Fe(II)- and 2-oxoglutarate-dependent halogenases (2ODHs) have been found to catalyze regio...
Main Authors: | Kim, Colin Y, Mitchell, Andrew J, Glinkerman, Christopher M, Li, Fu-Shuang, Pluskal, Tomáš, Weng, Jing-Ke |
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Other Authors: | Whitehead Institute for Biomedical Research |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2021
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Online Access: | https://hdl.handle.net/1721.1/134159 |
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