Spurious regulatory connections dictate the expression‐fitness landscape of translation factors
During steady-state cell growth, individual enzymatic fluxes can be directly inferred from growth rate by mass conservation, but the inverse problem remains unsolved. Perturbing the flux and expression of a single enzyme could have pleiotropic effects that may or may not dominate the impact on cell...
Main Authors: | Lalanne, Jean-Benoît, Parker, Darren J, Li, Gene-Wei |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
EMBO
2021
|
Online Access: | https://hdl.handle.net/1721.1/134184 |
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