HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes

© 2020 National Academy of Sciences. All rights reserved. Single-cell quantification of RNAs is important for understanding cellular heterogeneity and gene regulation, yet current approaches suffer from low sensitivity for individual transcripts, limiting their utility for many applications. Here we...

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Bibliographic Details
Main Authors: Marshall, Jamie L, Doughty, Benjamin R, Subramanian, Vidya, Guckelberger, Philine, Wang, Qingbo, Chen, Linlin M, Rodriques, Samuel G, Zhang, Kaite, Fulco, Charles P, Nasser, Joseph, Grinkevich, Elizabeth J, Noel, Teia, Mangiameli, Sarah, Bergman, Drew T, Greka, Anna, Lander, Eric S, Chen, Fei, Engreitz, Jesse M
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2021
Online Access:https://hdl.handle.net/1721.1/134185