Are redox changes a critical switch for mitotic progression?
Cell-cycle dependent redox changes result in increased protein oxidation in mitotic cells. We show that oxidative modifications of a conserved cysteine residue within Aurora A kinase (AURKA) can promote its activation during mitosis. Targeting redox-sensitive cysteine residues within AURKA may lead...
Main Authors: | , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Informa UK Limited
2021
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Online Access: | https://hdl.handle.net/1721.1/134407.2 |