Toxicogenomic analysis of a sustained release local anesthetic delivery system

Concerns over neurotoxicity have impeded the development of sustained release formulations providing prolonged duration local anesthesia (PDLA) from a single injection, for which there is an urgent clinical need. Here, we have used toxicogenomics to investigate whether nerve injury occurred during w...

Full description

Bibliographic Details
Main Authors: Shichor, Iris, Shomron, Noam, Lawlor, Michael W, Bae, Seul A, Zoldan, Janet, Langer, Robert, Kohane, Daniel S
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/134468