A mechanistic compartmental model for total antibody uptake in tumors
Antibodies are under development to treat a variety of cancers, such as lymphomas, colon, and breast cancer. A major limitation to greater efficacy for this class of drugs is poor distribution in vivo. Localization of antibodies occurs slowly, often in insufficient therapeutic amounts, and distribut...
Main Authors: | , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2022
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Online Access: | https://hdl.handle.net/1721.1/134471.2 |