Poly(ethylene glycol) with Observable Shedding
A FRET-bearing poly(ethylene glycol) (PEG) conjugate fluoresces at 520 nm when it is cleaved off nanoparticles (NPs; see picture). When the NPs were targeted on cancer cell lines, the reducing endosomal environment caused the cleavage of the disulfide bond and the shedding of the PEG layer. © 2010 W...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021
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| Online Access: | https://hdl.handle.net/1721.1/134534 |