Poly(ethylene glycol) with Observable Shedding

A FRET-bearing poly(ethylene glycol) (PEG) conjugate fluoresces at 520 nm when it is cleaved off nanoparticles (NPs; see picture). When the NPs were targeted on cancer cell lines, the reducing endosomal environment caused the cleavage of the disulfide bond and the shedding of the PEG layer. © 2010 W...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Gao, Weiwei, Langer, Robert, Farokhzad, Omid C
स्वरूप: लेख
भाषा:English
प्रकाशित: Wiley 2021
ऑनलाइन पहुंच:https://hdl.handle.net/1721.1/134534