Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair

Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair

© 2020 National Academy of Sciences. All rights reserved. Recent studies have implicated DNA polymerases θ (Pol θ) and β (Pol β) as mediators of alternative nonhomologous end-joining (Alt-NHEJ) events, including chromosomal translocations. Here we identify subunits of the replicative DNA polymerase...

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Bibliographic Details
Main Authors: Layer, Jacob V, Debaize, Lydie, Van Scoyk, Alexandria, House, Nealia C, Brown, Alexander J, Liu, Yunpeng, Stevenson, Kristen E, Hemann, Michael, Roberts, Steven A, Price, Brendan D, Weinstock, David M, Day, Tovah A
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2021
Online Access:https://hdl.handle.net/1721.1/134551

Internet

https://hdl.handle.net/1721.1/134551

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