Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
© 2020 American Association for Cancer Research. A hallmark of metastasis is the adaptation of tumor cells to new environments. Metabolic constraints imposed by the serine and glycine–limited brain environment restrict metastatic tumor growth. How brain metastases overcome these growth-prohibitive c...
| Format: | Article |
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| Language: | English |
| Published: |
American Association for Cancer Research (AACR)
2021
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| Online Access: | https://hdl.handle.net/1721.1/134555 |