One-Step Enzymatic Modification of the Cell Surface Redirects Cellular Cytotoxicity and Parasite Tropism

© 2014 American Chemical Society. Surface display of engineered proteins has many useful applications. The expression of a synthetic chimeric antigen receptor composed of an extracellular tumor-specific antibody fragment linked to a cytosolic activating motif in engineered T cells is now considered...

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Bibliographic Details
Main Authors: Swee, Lee Kim, Lourido, Sebastian, Bell, George W, Ingram, Jessica R, Ploegh, Hidde L
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: American Chemical Society (ACS) 2021
Online Access:https://hdl.handle.net/1721.1/134576