Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells
© 2017 Elsevier Ltd Current ISC culture systems face significant challenges such as animal-derived or undefined matrix compositions, batch-to-batch variability (e.g. Matrigel-based organoid culture), and complexity of assaying cell aggregates such as organoids which renders the research and clinical...
Main Authors: | Tong, Zhixiang, Martyn, Keir, Yang, Andy, Yin, Xiaolei, Mead, Benjamin E, Joshi, Nitin, Sherman, Nicholas E, Langer, Robert S, Karp, Jeffrey M |
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Format: | Article |
Language: | English |
Published: |
Elsevier BV
2021
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Online Access: | https://hdl.handle.net/1721.1/134688 |
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