A 3D microvascular network model to study the impact of hypoxia on the extravasation potential of breast cell lines

© 2018, The Author(s). Hypoxia is a common feature of the tumor microenvironment. Accumulating evidence has demonstrated hypoxia to be an important trigger of tumor cell invasion or metastasizes via hypoxia-signaling cascades, including hypoxia-inducible factors (HIFs). Microfluidic model can be a r...

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Bibliographic Details
Main Authors: Song, Jiho, Miermont, Agnès, Lim, Chwee Teck, Kamm, Roger D
Format: Article
Published: Springer Nature 2021
Online Access:https://hdl.handle.net/1721.1/134893