Rational design of thiolase substrate specificity for metabolic engineering applications

© 2018 Wiley Periodicals, Inc. Metabolic engineering efforts require enzymes that are both highly active and specific toward the synthesis of a desired output product to be commercially feasible. The 3-hydroxyacid (3HA) pathway, also known as the reverse β-oxidation or coenzyme-A-dependent chain-elo...

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Bibliographic Details
Main Authors: Bonk, Brian M, Tarasova, Yekaterina, Hicks, Michael A, Tidor, Bruce, Prather, Kristala LJ
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Wiley 2021
Online Access:https://hdl.handle.net/1721.1/134936