Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to each of the Murine FcγR Types

Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to each of the Murine FcγR Types

© 2018 Elsevier Ltd We have engineered a panel of novel Fn3 scaffold-based proteins that bind with high specificity and affinity to each of the individual mouse Fcγ receptors (mFcγR). These binders were expressed as fusions to anti-tumor antigen single-chain antibodies and mouse serum albumin, creat...

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Bibliographic Details
Main Authors: Chen, Tiffany F, Li, Kevin K, Zhu, Eric F, Opel, Cary F, Kauke, Monique J, Kim, Heeyoon, Atolia, Eta, Wittrup, K Dane
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/134976

Internet

https://hdl.handle.net/1721.1/134976

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