Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to each of the Murine FcγR Types
© 2018 Elsevier Ltd We have engineered a panel of novel Fn3 scaffold-based proteins that bind with high specificity and affinity to each of the individual mouse Fcγ receptors (mFcγR). These binders were expressed as fusions to anti-tumor antigen single-chain antibodies and mouse serum albumin, creat...
Main Authors: | Chen, Tiffany F, Li, Kevin K, Zhu, Eric F, Opel, Cary F, Kauke, Monique J, Kim, Heeyoon, Atolia, Eta, Wittrup, K Dane |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2021
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Online Access: | https://hdl.handle.net/1721.1/134976 |
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