Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA

Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA

© 2018, The Author(s). Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a well-characterized tumour-suppressor gene that is lost or mutated in about half of metastatic castration-resistant prostate cancers and in many other human cancers. The restoration of functional PTEN as a tr...

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Bibliographic Details
Main Authors: Islam, Mohammad Ariful, Xu, Yingjie, Tao, Wei, Ubellacker, Jessalyn M, Lim, Michael, Aum, Daniel, Lee, Gha Young, Zhou, Kun, Zope, Harshal, Yu, Mikyung, Cao, Wuji, Oswald, James Trevor, Dinarvand, Meshkat, Mahmoudi, Morteza, Langer, Robert, Kantoff, Philip W, Farokhzad, Omid C, Zetter, Bruce R, Shi, Jinjun
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/135009

Internet

https://hdl.handle.net/1721.1/135009

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