A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action

A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action

© 2019 Elsevier Inc. Current machine learning techniques enable robust association of biological signals with measured phenotypes, but these approaches are incapable of identifying causal relationships. Here, we develop an integrated “white-box” biochemical screening, network modeling, and machine l...

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Bibliographic Details
Main Authors: Yang, Jason H, Wright, Sarah N, Hamblin, Meagan, McCloskey, Douglas, Alcantar, Miguel A, Schrübbers, Lars, Lopatkin, Allison J, Satish, Sangeeta, Nili, Amir, Palsson, Bernhard O, Walker, Graham C, Collins, James J
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/135182

Internet

https://hdl.handle.net/1721.1/135182

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