A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action
© 2019 Elsevier Inc. Current machine learning techniques enable robust association of biological signals with measured phenotypes, but these approaches are incapable of identifying causal relationships. Here, we develop an integrated “white-box” biochemical screening, network modeling, and machine l...
Main Authors: | Yang, Jason H, Wright, Sarah N, Hamblin, Meagan, McCloskey, Douglas, Alcantar, Miguel A, Schrübbers, Lars, Lopatkin, Allison J, Satish, Sangeeta, Nili, Amir, Palsson, Bernhard O, Walker, Graham C, Collins, James J |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2021
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Online Access: | https://hdl.handle.net/1721.1/135182 |
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