Targeting the cyclin-dependent kinase 5 in metastatic melanoma

Targeting the cyclin-dependent kinase 5 in metastatic melanoma

© 2020 National Academy of Sciences. All rights reserved. The cyclin-dependent kinase 5 (CDK5), originally described as a neuronal-specific kinase, is also frequently activated in human cancers. Using conditional CDK5 knockout mice and a mouse model of highly metastatic melanoma, we found that CDK5...

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Main Authors: Sharma, Samanta, Zhang, Tian, Michowski, Wojciech, Rebecca, Vito W, Xiao, Min, Ferretti, Roberta, Suski, Jan M, Bronson, Roderick T, Paulo, Joao A, Frederick, Dennie, Fassl, Anne, Boland, Genevieve M, Geng, Yan, Lees, Jacqueline A, Medema, Rene H, Herlyn, Meenhard, Gygi, Steven P, Sicinski, Piotr
其他作者: Koch Institute for Integrative Cancer Research at MIT
格式: 文件
语言:English
出版: Proceedings of the National Academy of Sciences 2021
在线阅读:https://hdl.handle.net/1721.1/135192

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https://hdl.handle.net/1721.1/135192

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