Phosphocholine accumulation and PHOSPHO1 depletion promote adipose tissue thermogenesis

© 2020 National Academy of Sciences. All rights reserved. Phosphocholine phosphatase-1 (PHOSPHO1) is a phosphocholine phosphatase that catalyzes the hydrolysis of phosphocholine (PC) to choline. Here we demonstrate that the PHOSPHO1 transcript is highly enriched in mature brown adipose tissue (BAT)...

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Bibliographic Details
Main Authors: Jiang, Mengxi, Chavarria, Tony E, Yuan, Bingbing, Lodish, Harvey F, Huang, Nai-Jia
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2021
Online Access:https://hdl.handle.net/1721.1/135216