Gut CD4<sup>+</sup> T cell phenotypes are a continuum molded by microbes, not by T<inf>H</inf> archetypes
CD4 effector lymphocytes (T ) are traditionally classified by the cytokines they produce. To determine the states that T cells actually adopt in frontline tissues in vivo, we applied single-cell transcriptome and chromatin analyses to colonic T cells in germ-free or conventional mice or in mice a...
| Format: | Article |
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| Language: | English |
| Published: |
Springer Science and Business Media LLC
2021
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| Online Access: | https://hdl.handle.net/1721.1/135272 |