A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density

A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density

Nasa Sinnott-Armstrong and colleagues identify a pleiotropic risk locus at 3q21 that is associated with type 2 diabetes (T2D) and greater bone mineral density (BMD) and its associated cell-autonomous mechanisms in adipocytes and osteoblasts. Together, these findings provide a possible explanation fo...

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Bibliographic Details
Main Authors: Sinnott-Armstrong, Nasa, Sousa, Isabel S., Laber, Samantha, Rendina-Ruedy, Elizabeth, Nitter Dankel, Simon E., Ferreira, Teresa, Mellgren, Gunnar, Karasik, David, Rivas, Manuel, Pritchard, Jonathan, Guntur, Anyonya R., Cox, Roger D., Lindgren, Cecilia M., Hauner, Hans, Sallari, Richard, Rosen, Clifford J., Hsu, Yi-Hsiang, Lander, Eric S., Kiel, Douglas P., Claussnitzer, Melina
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/135273.2

Internet

https://hdl.handle.net/1721.1/135273.2

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