MCART1/SLC25A51 is required for mitochondrial NAD transport

The nicotinamide adenine dinucleotide (NAD /NADH) pair is a cofactor in redox reactions and is particularly critical in mitochondria as it connects substrate oxidation by the tricarboxylic acid (TCA) cycle to adenosine triphosphate generation by the electron transport chain (ETC) and oxidative phosp...

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Bibliographic Details
Main Authors: Kory, Nora, uit de Bos, Jelmi, van der Rijt, Sanne, Jankovic, Nevena, Güra, Miriam, Arp, Nicholas, Pena, Izabella A, Prakash, Gyan, Chan, Sze Ham, Kunchok, Tenzin, Lewis, Caroline A, Sabatini, David M
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/135285