Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages

Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages

© 2020, The Author(s). Macrophages play an essential role in the early immune response against Toxoplasma and are the cell type preferentially infected by the parasite in vivo. Interferon gamma (IFNγ) elicits a variety of anti-Toxoplasma activities in macrophages. Using a genome-wide CRISPR screen w...

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Bibliographic Details
Main Authors: Wang, Yifan, Sangaré, Lamba Omar, Paredes-Santos, Tatiana C, Hassan, Musa A, Krishnamurthy, Shruthi, Furuta, Anna M, Markus, Benedikt M, Lourido, Sebastian, Saeij, Jeroen PJ
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/135295

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https://hdl.handle.net/1721.1/135295

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