Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice

© 2020, The Author(s). Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in the Fmr1-/y mouse model of fragile X (FX) suggests that increased constitut...

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Bibliographic Details
Main Authors: Thomazeau, Aurore, Bosch, Miquel, Essayan-Perez, Sofia, Barnes, Stephanie A, De Jesus-Cortes, Hector, Bear, Mark F
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/135318