Profiling DNA break sites and transcriptional changes in response to contextual fear learning

<jats:p>Neuronal activity generates DNA double-strand breaks (DSBs) at specific loci <jats:italic>in vitro</jats:italic> and this facilitates the rapid transcriptional induction of early response genes (ERGs). Physiological neuronal activity, including exposure of mice to learning...

Full description

Bibliographic Details
Main Authors: Stott, Ryan T, Kritsky, Oleg, Tsai, Li-Huei
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021
Online Access:https://hdl.handle.net/1721.1/135342