Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility

Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility

© 2020, The Author(s). Artemisinins have revolutionized the treatment of Plasmodium falciparum malaria; however, resistance threatens to undermine global control efforts. To broadly explore artemisinin susceptibility in apicomplexan parasites, we employ genome-scale CRISPR screens recently developed...

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Bibliographic Details
Main Authors: Harding, Clare R, Sidik, Saima M, Petrova, Boryana, Gnädig, Nina F, Okombo, John, Herneisen, Alice L, Ward, Kurt E, Markus, Benedikt M, Boydston, Elizabeth A, Fidock, David A, Lourido, Sebastian
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/135382

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https://hdl.handle.net/1721.1/135382

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