Weak acids as an alternative anti-microbial therapy

Weak acids such as acetic acid and N-acetyl cysteine (NAC) at pH less than their pKa can effectively eradicate biofilms due to their ability to penetrate the biofilm matrix and the cell membrane. However, the optimum conditions for their activity against drug resistant strains, and safety, need to b...

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Bibliographic Details
Main Authors: Kundukad, Binu, Udayakumar, Gayathri, Grela, Erin, Kaur, Dhamanpreet, Rice, Scott A, Kjelleberg, Staffan, Doyle, Patrick S
Other Authors: Singapore-MIT Alliance in Research and Technology (SMART)
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/135423