Weak acids as an alternative anti-microbial therapy
Weak acids such as acetic acid and N-acetyl cysteine (NAC) at pH less than their pKa can effectively eradicate biofilms due to their ability to penetrate the biofilm matrix and the cell membrane. However, the optimum conditions for their activity against drug resistant strains, and safety, need to b...
Main Authors: | Kundukad, Binu, Udayakumar, Gayathri, Grela, Erin, Kaur, Dhamanpreet, Rice, Scott A, Kjelleberg, Staffan, Doyle, Patrick S |
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Other Authors: | Singapore-MIT Alliance in Research and Technology (SMART) |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2021
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Online Access: | https://hdl.handle.net/1721.1/135423 |
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