The Intrinsically Disordered N-terminal Extension of the ClpS Adaptor Reprograms Its Partner AAA + ClpAP Protease

© 2020 Adaptor proteins modulate substrate selection by AAA + proteases. The ClpS adaptor delivers N-degron substrates to ClpAP but inhibits degradation of substrates bearing ssrA tags or other related degrons. How ClpS inhibits degradation of such substrates is poorly understood. Here, we demonstra...

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Bibliografiske detaljer
Main Authors: Torres-Delgado, Amaris, Kotamarthi, Hema Chandra, Sauer, Robert T, Baker, Tania A
Andre forfattere: Massachusetts Institute of Technology. Department of Biology
Format: Article
Sprog:English
Udgivet: Elsevier BV 2021
Online adgang:https://hdl.handle.net/1721.1/135455