A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution
© 2020, The Author(s). Aneuploidy is a feature of many cancers. Recent studies demonstrate that in the hematopoietic stem and progenitor cell (HSPC) compartment aneuploid cells have reduced fitness and are efficiently purged from the bone marrow. However, early phases of hematopoietic reconstitution...
Main Authors: | , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2021
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Online Access: | https://hdl.handle.net/1721.1/135466 |