Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice

<jats:p>Following curative immunotherapy of B16F10 tumors, ~60% of mice develop a strong antibody response against cell-surface tumor antigens. Their antisera confer prophylactic protection against intravenous challenge with B16F10 cells, and also cross-react with syngeneic and allogeneic tumo...

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Bibliographic Details
Main Authors: Kang, Byong H, Momin, Noor, Moynihan, Kelly D, Silva, Murillo, Li, Yingzhong, Irvine, Darrell J, Wittrup, K Dane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021
Online Access:https://hdl.handle.net/1721.1/135528