Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads

<jats:p>Immunotherapies are a promising advance in cancer treatment. However, because only a subset of cancer patients benefits from these treatments it is important to find mechanisms that will broaden the responding patient population. Generally, tumors with high mutational burdens have the...

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Bibliographic Details
Main Authors: Lussier, Danielle M, Alspach, Elise, Ward, Jeffrey P, Miceli, Alexander P, Runci, Daniele, White, J Michael, Mpoy, Cedric, Arthur, Cora D, Kohlmiller, Heather N, Jacks, Tyler, Artyomov, Maxim N, Rogers, Buck E, Schreiber, Robert D
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2021
Online Access:https://hdl.handle.net/1721.1/135643