Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling

Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling

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<jats:title>Abstract</jats:title><jats:p>The mechanistic target of rapamycin complex 1 (mTORC1) integrates cellular nutrient signaling and hormonal cues to control metabolism. We have previously shown that constitutive nutrient signaling to mTORC1 by means of genetic activation of...

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Bibliographic Details
Main Authors: de la Calle Arregui, Celia, Plata-Gómez, Ana Belén, Deleyto-Seldas, Nerea, García, Fernando, Ortega-Molina, Ana, Abril-Garrido, Julio, Rodriguez, Elena, Nemazanyy, Ivan, Tribouillard, Laura, de Martino, Alba, Caleiras, Eduardo, Campos-Olivas, Ramón, Mulero, Francisca, Laplante, Mathieu, Muñoz, Javier, Pende, Mario, Sabio, Guadalupe, Sabatini, David M, Efeyan, Alejo
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/135647

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https://hdl.handle.net/1721.1/135647

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