The CCL2-CCR2 astrocyte-cancer cell axis in tumor extravasation at the brain

<jats:p>Although brain metastases are common in cancer patients, little is known about the mechanisms of cancer extravasation across the blood-brain barrier (BBB), a key step in the metastatic cascade that regulates the entry of cancer cells into the brain parenchyma. Here, we show, in a three...

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Bibliographic Details
Main Authors: Hajal, Cynthia, Shin, Yoojin, Li, Leanne, Serrano, Jean Carlos, Jacks, Tyler, Kamm, Roger D
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/135665