Commensal epitopes drive differentiation of colonic T regs

© 2020 The Authors. The gut microbiome is the largest source of intrinsic non-self-antigens that are continuously sensed by the immune system but typically do not elicit lymphocyte responses. CD4+ T cells are critical to sustain uninterrupted tolerance to microbial antigens and to prevent intestinal...

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Bibliographic Details
Main Authors: Kuczma, Michal P, Szurek, Edyta A, Cebula, Anna, Chassaing, Benoit, Jung, Yu-Jin, Kang, Sang-Moo, Fox, James G, Stecher, Bärbel, Ignatowicz, Leszek
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/135693