The development of colitis in Il10−/− mice is dependent on IL-22

© 2020, Society for Mucosal Immunology. Mice deficient in the IL-10 pathway are the most widely used models of intestinal immunopathology. IL-17A is strongly implicated in gut disease in mice and humans, but conflicting evidence has drawn IL-17’s role in the gut into question. IL-22 regulates antimi...

Full description

Bibliographic Details
Main Authors: Gunasekera, Dilini C, Ma, Jinxia, Vacharathit, Vimvara, Shah, Palak, Ramakrishnan, Amritha, Uprety, Priyanka, Shen, Zeli, Sheh, Alexander, Brayton, Cory F, Whary, Mark T, Fox, James G, Bream, Jay H
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/135695