HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

SARS-CoV-2 infects epithelial cells of the human gastrointestinal (GI) tract and causes related symptoms. HIV infection impairs gut homeostasis and is associated with an increased risk of COVID-19 fatality. To investigate the potential link between these observations, we analyzed single-cell transcr...

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Bibliographic Details
Main Authors: Fardoos, Rabiah, Asowata, Osaretin E, Herbert, Nicholas, Nyquist, Sarah K, Zungu, Yenzekile, Singh, Alveera, Ngoepe, Abigail, Mbano, Ian M, Mthabela, Ntombifuthi, Ramjit, Dirhona, Karim, Farina, Kuhn, Warren, Madela, Fusi G, Manzini, Vukani T, Anderson, Frank, Berger, Bonnie, Pers, Tune H, Shalek, Alex K, Leslie, Alasdair, Kløverpris, Henrik N
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: American Society for Clinical Investigation 2021
Online Access:https://hdl.handle.net/1721.1/135773

Internet

https://hdl.handle.net/1721.1/135773

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