Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids

Copyright © 2020 American Chemical Society. Antisense oligonucleotide therapies are important cancer treatments, which can suppress genes in cancer cells that are critical for cell survival. SF3B1 has recently emerged as a promising gene target that encodes a key splicing factor in the SF3B protein...

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Bibliographic Details
Main Authors: Lu, Zeyu, Paolella, Brenton R., Truex, Nicholas L., Loftis, Alexander R., Liao, Xiaoli, Rabideau, Amy E., Brown, Meredith S., Busanovich, John, Beroukhim, Rameen, Pentelute, Bradley L.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2022
Online Access:https://hdl.handle.net/1721.1/135910.2