A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb+/− rats

© 2020 The authors Tumors caused by loss-of-function mutations in genes encoding TCA cycle enzymes have been recently discovered and are now of great interest. Mutations in succinate dehydrogenase (SDH) subunits cause pheochromocytoma/paraganglioma (PCPG) and syndromically associated tumors, which d...

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Bibliographic Details
Main Authors: Powers, James F, Cochran, Brent, Baleja, James D, Sikes, Hadley D, Pattison, Andrew D, Zhang, Xue, Lomakin, Inna, Shepard-Barry, Annette, Pacak, Karel, Moon, Sun Jin, Langford, Troy F, Stein, Kassi Taylor, Tothill, Richard W, Ouyang, Yingbin, Tischler, Arthur S
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Bioscientifica 2021
Online Access:https://hdl.handle.net/1721.1/135930