APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

© 2020, The Author(s). The ε4 allele of apolipoprotein E (APOE) is the dominant genetic risk factor for late-onset Alzheimer’s disease (AD). However, the reason for the association between APOE4 and AD remains unclear. While much of the research has focused on the ability of the apoE4 protein to inc...

Full description

Bibliographic Details
Main Authors: Area-Gomez, Estela, Larrea, Delfina, Pera, Marta, Agrawal, Rishi R., Guilfoyle, David N., Pirhaji, Leila, Shannon, Kathleen, Arain, Hirra A., Ashok, Archana, Chen, Qiuying, Dillman, Allissa A., Figueroa, Helen Y., Cookson, Mark R., Gross, Steven S., Fraenkel, Ernest, Duff, Karen E., Nuriel, Tal
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2022
Online Access:https://hdl.handle.net/1721.1/135943.2