Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines

© 2020, The Author(s), under exclusive licence to Springer Nature Limited. The formulations of peptide-based antitumour vaccines being tested in clinical studies are generally associated with weak potency. Here, we show that pharmacokinetically tuning the responses of peptide vaccines by fusing the...

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Bibliographic Details
Main Authors: Mehta, Naveen K, Pradhan, Roma V, Soleimany, Ava P, Moynihan, Kelly D, Rothschilds, Adrienne M, Momin, Noor, Rakhra, Kavya, Mata-Fink, Jordi, Bhatia, Sangeeta N, Wittrup, K Dane, Irvine, Darrell J
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/135964